Instituto de Química Orgánica General -ko ikertzaileekin lankidetzan egindako argitalpenak (81)

2025

  1. 2-{N-[ω-(1-Benzylpiperidin-4-yl)alkyl]amino}-6-[(prop-2-yn-1-yl)amino]pyridine-3,5-dicarbonitriles Showing High Affinity for σ1/2 Receptors

    International Journal of Molecular Sciences, Vol. 26, Núm. 3

2024

  1. Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases

    Journal of Medicinal Chemistry, Vol. 67, Núm. 18, pp. 16533-16555

  2. Contilistat, a New Multitarget Small Polyfunctionalized Indole Derivative

    Synlett

  3. Discovery of New Highly Potent Histamine H3 Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors

    ACS Chemical Neuroscience, Vol. 15, Núm. 18, pp. 3363-3383

2023

  1. Evaluation of the Lysyl Oxidase-Like 2 (LOXL2) inhibitory activity of pimaranes and their glycosyl derivatives

    Biomedical and Biopharmaceutical Research, Vol. 20, Núm. 1, pp. 13-24

  2. Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer’s Disease Treatment

    International Journal of Molecular Sciences, Vol. 24, Núm. 11

  3. PLECTRANTHUS: FROM TRADITIONAL MEDICINE TO BRAIN TUMOR THERAPY WITH DITERPENES

    Journal of Research in Pharmacy, Vol. 27, pp. 9-11

  4. Straightforward Synthesis of Bis[(trifluoromethyl)sulfonyl]ethylated Isocoumarins from 2-Ethynylbenzoates

    Journal of Organic Chemistry, Vol. 88, Núm. 11, pp. 7373-7380

2022

  1. N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

    Molecules, Vol. 27, Núm. 21

  2. Phytochemical Study and Antiglioblastoma Activity Assessment of Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger var. hadiensis Stems

    Molecules, Vol. 27, Núm. 12

  3. The Chemotype of Chromanones as a Privileged Scaffold for Multineurotarget Anti-Alzheimer Agents

    ACS Pharmacology and Translational Science, Vol. 5, Núm. 11, pp. 1097-1108

2021

  1. Pd-catalyzed C(sp3)-C(sp) bond formation in iodocyclobutenes

    Chemical Communications, Vol. 57, Núm. 68, pp. 8456-8459

  2. Privileged quinolylnitrones for the combined therapy of ischemic stroke and alzheimer’s disease

    Pharmaceuticals, Vol. 14, Núm. 9

  3. Studies on the affinity of 6-[(: N -(cyclo)aminoalkyl)oxy]-4 H -chromen-4-ones for sigma 1/2 receptors

    RSC Medicinal Chemistry, Vol. 12, Núm. 6, pp. 1000-1004

  4. Synthesis and Biological Assessment of PyrimidoTacrines as Promising Agents for Alzheimer's Disease Therapy

    ChemistrySelect, Vol. 6, Núm. 37, pp. 9975-9980

  5. Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments

    Chemical Record, Vol. 21, Núm. 1, pp. 162-174

2020

  1. Acetylcholinesterase inhibition of diversely functionalized quinolinones for alzheimer’s disease therapy

    International Journal of Molecular Sciences, Vol. 21, Núm. 11, pp. 1-20

  2. Automated Synthesis of New Quinoxalinetacrines

    ChemistrySelect, Vol. 5, Núm. 21, pp. 6491-6493

  3. In Vitro and in Silico ADME-Tox Profiling and Safety Significance of Multifunctional Monoamine Oxidase Inhibitors Targeting Neurodegenerative Diseases

    ACS Chemical Neuroscience, Vol. 11, Núm. 22, pp. 3793-3801

  4. Synthesis of hantzsch adducts as cholinesterases and calcium flux inhibitors, antioxidants and neuroprotectives

    International Journal of Molecular Sciences, Vol. 21, Núm. 20, pp. 1-19