Physicochemical considerations of ibuprofen and its sodium salt in different solvents
- M. Ángeles Peña Fernández 1
- Mathew B 1
- Norma Sofía Torres Pabón 1
- 1 Departamento de Ciencias Biomédicas, U.D. Farmacia y Tecnología Farmacéutica. Universidad de Alcalá. Alcalá de Henares. Madrid.
ISSN: 2660-6356
Datum der Publikation: 2021
Titel der Ausgabe: XV CONGRESO DE LA SOCIEDAD ESPAÑOLA DE FARMACIA INDUSTRIA Y GALÉNICA
Ausgabe: 2
Nummer: 2
Seiten: 170-172
Art: Artikel
Andere Publikationen in: RESCIFAR Revista Española de Ciencias Farmacéuticas
Zusammenfassung
From a pharmaceutical point of view, one of the most significant actions is the physicochemical information through characterization of the pharmacologically active molecules. This paper deals about characterization of some aspects of racemic compound (R,S)-(±)-ibuprofen or (R,S)- (±)-2-(4-isobutylphenyl) propionic acid (IBP) and (R,S)-(±)-ibuprofen salt, ibuprofen (IBPNa) [1-3], using solvent precipitation method with different types of instrumental analysis, to describe the possible differences detected respect crystallization, polymorphic conversion, desolvation or dehydration.