
Sergio de
Frutos García
Profesor/a Ayudante Doctor/a
Publications (45) Sergio de Frutos García publications
2025
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Integrin-Linked Kinase (ILK) Promotes Mitochondrial Dysfunction by Decreasing CPT1A Expression in a Folic Acid-Based Model of Kidney Disease
International Journal of Molecular Sciences, Vol. 26, Núm. 5
2024
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A Graphene-Based Bioactive Product with a Non-Immunological Impact on Mononuclear Cell Populations from Healthy Volunteers
Nanomaterials, Vol. 14, Núm. 23
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Integrin-linked kinase mRNA expression in circulating mononuclear cells as a biomarker of kidney and vascular damage in experimental chronic kidney disease
Cell Communication and Signaling, Vol. 22, Núm. 1
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La fibrosis y disfunción mitocondrial en el daño renal inducido por ácido fólico revierte con la delección de ILK
Dianas: revista de dianas terapéuticas, Vol. 13, Núm. 1
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La inhibición de calpaína previene la fibrosis mediada por Smad en la enfermedad renal crónica.
Dianas: revista de dianas terapéuticas, Vol. 13, Núm. 1
2023
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A new graphene-based nanomaterial increases lipolysis and reduces body weight gain through integrin linked kinase (ILK)
Biomaterials Science, Vol. 11, Núm. 14, pp. 4916-4929
2022
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Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation
Experimental and Molecular Medicine, Vol. 54, Núm. 3, pp. 226-238
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The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo
Cell and Bioscience, Vol. 12, Núm. 1
2021
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Tripeptides as Integrin-Linked Kinase Modulating Agents Based on a Protein-Protein Interaction with α-Parvin
ACS Medicinal Chemistry Letters, Vol. 12, Núm. 11, pp. 1656-1662
2020
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Incremento de calpaínas 1 y 2 durante el desarrollo de enfermedad renal crónica en ratones alimentados con una dieta rica en adenina
Dianas: revista de dianas terapéuticas, Vol. 9, Núm. 1
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Integrin linked kinase (ILK) downregulation as an early event during the development of metabolic alterations in a short-term high fat diet mice model
Cellular Physiology and Biochemistry, Vol. 54, Núm. 1, pp. 71-87
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La formación de podosomas y la adhesión de leucocitos es mediada por la quinasa ligada a integrinas en la enfermedad renal crónica (ERC)
Dianas: revista de dianas terapéuticas, Vol. 9, Núm. 1
2019
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Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression
Biochimica et Biophysica Acta - Molecular Basis of Disease, Vol. 1865, Núm. 6, pp. 1284-1297
2018
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Contribution of uremic toxins to the vascular fibrosis associated with chronic kidney disease
Nefrologia, Vol. 38, Núm. 6, pp. 639-646
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H-ras deletion protects against angiotensin II-induced arterial hypertension and cardiac remodeling through protein kinase G-Iβ pathway activation
FASEB Journal, Vol. 32, Núm. 2, pp. 920-934
2017
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Display of the Albumin-Binding Domain in the Envelope Improves Lentiviral Vector Bioavailability
Human Gene Therapy Methods, Vol. 28, Núm. 6, pp. 340-351
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Integrin linked kinase regulates the transcription of AQP2 by NFATC3
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, Vol. 1860, Núm. 9, pp. 922-935
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Peripheral insulin resistance in ILK-depleted mice by reduction of GLUT4 expression
Journal of Endocrinology, Vol. 234, Núm. 2, pp. 115-128
2016
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Erratum: HSP70 increases extracellular matrix production by human vascular smooth muscle through TGF-β1 up-regulation (International Journal of Biochemistry and Cell Biology (2013)45 (232-242))
International Journal of Biochemistry and Cell Biology
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ILK and cytoskeletal architecture: An important determinant of AQP2 recycling and subsequent entry into the exocytotic pathway
American Journal of Physiology - Renal Physiology, Vol. 311, Núm. 6, pp. F1346-F1357