Novel strategies for the treatment of visceral pain. Role of voltage-gated sodium channels and enhancement of the opioid-induced analgesia by selective blockade of sigma-1 receptor
- Artacho Cordón, Antonia
- Cruz Miguel Cendán Martínez Doktorvater/Doktormutter
Universität der Verteidigung: Universidad de Granada
Fecha de defensa: 05 von April von 2022
- José Manuel Baeyens Cabrera Präsident/in
- Enrique José Cobos del Moral Sekretär/in
- Lydia Jiménez Díaz Vocal
- Carolina Laura Roza Fernández de Caleya Vocal
- Enrique Portillo Salido Vocal
Art: Dissertation
Zusammenfassung
The first goal of this Thesis was to evaluate the antinociceptive effects of TTXin three different visceral pain models in mice: the intracolonic administration of both capsaicin and mustard oil; and a model of cyclophosphamideinduced cystitis.