Novel strategies for the treatment of visceral pain. Role of voltage-gated sodium channels and enhancement of the opioid-induced analgesia by selective blockade of sigma-1 receptor
- Artacho Cordón, Antonia
- Cruz Miguel Cendán Martínez Zuzendaria
Defentsa unibertsitatea: Universidad de Granada
Fecha de defensa: 2022(e)ko apirila-(a)k 05
- José Manuel Baeyens Cabrera Presidentea
- Enrique José Cobos del Moral Idazkaria
- Lydia Jiménez Díaz Kidea
- Carolina Laura Roza Fernández de Caleya Kidea
- Enrique Portillo Salido Kidea
Mota: Tesia
Laburpena
The first goal of this Thesis was to evaluate the antinociceptive effects of TTXin three different visceral pain models in mice: the intracolonic administration of both capsaicin and mustard oil; and a model of cyclophosphamideinduced cystitis.