Novel strategies for the treatment of visceral pain. Role of voltage-gated sodium channels and enhancement of the opioid-induced analgesia by selective blockade of sigma-1 receptor
- Artacho Cordón, Antonia
- Cruz Miguel Cendán Martínez Director
Defence university: Universidad de Granada
Fecha de defensa: 05 April 2022
- José Manuel Baeyens Cabrera Chair
- Enrique José Cobos del Moral Secretary
- Lydia Jiménez Díaz Committee member
- Carolina Laura Roza Fernández de Caleya Committee member
- Enrique Portillo Salido Committee member
Type: Thesis
Abstract
The first goal of this Thesis was to evaluate the antinociceptive effects of TTXin three different visceral pain models in mice: the intracolonic administration of both capsaicin and mustard oil; and a model of cyclophosphamideinduced cystitis.