Protocolo diagnóstico y terapéutico de las poliglobulias
- García Ramírez, P. 1
- Villafuerte Gutiérrez, P. 1
- 1 Servicio de Hematología y Hemoterapia, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España
ISSN: 0304-5412
Argitalpen urtea: 2020
Saila: 13
Zenbakia: 21
Orrialdeak: 1224-1228
Mota: Artikulua
Beste argitalpen batzuk: Medicine: Programa de Formación Médica Continuada Acreditado
Garapen Iraunkorreko Helburuak
Laburpena
Polycythemia or erythrocytosis refers to an increase in hemoglobin and hematocrit concentration in peripheral blood. The erythopoietin, produced in 95% of renal cells, is in charge of erythropoiesis regulation due to hypoxia and is elevated in secondary erythrocytosis. The most important primary erythrocytosis is polycythemia vera, a chronic myeloproliferative neoplasm that produces erythrocytosis independently of erythropoietin due to a mutation in erythroid progenitor cells. A diagnosis is established based on an increase in hemoglobin above 16.5 g/dl in men and 16 g/dl in women. An etiological diagnosis is fundamental for an appropriate management of the patient.
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