Protocolo diagnóstico y terapéutico de las poliglobulias
- García Ramírez, P. 1
- Villafuerte Gutiérrez, P. 1
- 1 Servicio de Hematología y Hemoterapia, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, España
ISSN: 0304-5412
Ano de publicación: 2020
Serie: 13
Número: 21
Páxinas: 1224-1228
Tipo: Artigo
Outras publicacións en: Medicine: Programa de Formación Médica Continuada Acreditado
Obxectivos de Desenvolvemento Sustentable
Resumo
Polycythemia or erythrocytosis refers to an increase in hemoglobin and hematocrit concentration in peripheral blood. The erythopoietin, produced in 95% of renal cells, is in charge of erythropoiesis regulation due to hypoxia and is elevated in secondary erythrocytosis. The most important primary erythrocytosis is polycythemia vera, a chronic myeloproliferative neoplasm that produces erythrocytosis independently of erythropoietin due to a mutation in erythroid progenitor cells. A diagnosis is established based on an increase in hemoglobin above 16.5 g/dl in men and 16 g/dl in women. An etiological diagnosis is fundamental for an appropriate management of the patient.
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